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Validity of self-reported stroke in elderly African Americans, Caribbean Hispanics, and Whites

TitleValidity of self-reported stroke in elderly African Americans, Caribbean Hispanics, and Whites
Publication TypeJournal Article
Year of Publication2009
AuthorsReitz, C, Schupf, N, Luchsinger, JA, Brickman, AM, Manly, JJ, Andrews, H, Tang, MX, DeCarli, C, Brown, TR, Mayeux, R
JournalArchives of NeurologyArchives of Neurology
Date PublishedJul
ISBN Number0003-9942<br/>1538-3687
Accession NumberPeer Reviewed Journal: 2009-10610-004
Keywords*Blacks, *Cerebrovascular Accidents, *Diagnosis, *Latinos/Latinas, *Whites, Geriatric Patients, Human Male Female Adulthood (18 yrs & older) Aged (65 yrs & older), Neurological Disorders & Brain Damage [3297], Self Report, self-reported stroke, diagnosis, elderly patients, African Americans, Caribbean Hispanics, Whites, us
AbstractBackground: The validity of a self-reported stroke remains inconclusive. Objective: To validate the diagnosis of self-reported stroke using stroke identified by magnetic resonance imaging (MRI) as the standard. Design, Setting, and Participants: Community-based cohort study of nondemented, ethnically diverse elderly persons in northern Manhattan. Methods: High-resolution quantitative MRIs were acquired for 717 participants without dementia. Sensitivity and specificity of stroke by self-report were examined using cross-sectional analyses and the 2 test. Putative relationships between factors potentially influencing the reporting of stroke, including memory performance, cognitive function, and vascular risk factors, were assessed using logistic regression models. Subsequently, all analyses were repeated, stratified by age, sex, ethnic group, and level of education. Results: In analyses of the whole sample, sensitivity of stroke self-report for a diagnosis of stroke on MRI was 32.4%, and specificity was 78.9%. In analyses stratified by median age (80.1 years), the validity between reported stroke and detection of stroke on MRI was significantly better in the younger than the older age group (for all vascular territories: sensitivity and specificity, 36.7% and 81.3% vs 27.6% and 26.2%; P = .02). Impaired memory, cognitive skills, or language ability and the presence of hypertension or myocardial infarction were associated with higher rates of false-negative results. Conclusions: Using brain MRI as the standard, specificity and sensitivity of stroke self-report are low. Accuracy of self-report is influenced by age, presence of vascular disease, and cognitive function. In stroke research, sensitive neuroimaging techniques rather than stroke self-report should be used to determine stroke history. (PsycINFO Database Record (c) 2013 APA, all rights reserved) (journal abstract).