| Title | Uric acid, hypertension, and chronic kidney disease among Alaska Eskimos: the Genetics of Coronary Artery Disease in Alaska Natives (GOCADAN) study |
| Publication Type | Journal Article |
| Year of Publication | 2012 |
| Authors | Jolly, SE, Mete, M, Wang, H, Zhu, J, Ebbesson, SO, Voruganti, VS, Comuzzie, AG, Howard, BV, Umans, JG |
| Journal | J Clin Hypertens (Greenwich)J Clin Hypertens (Greenwich) |
| Volume | 14 |
| Pagination | 71-7 |
| Date Published | Feb |
| ISBN Number | 1751-7176 (Electronic)<br/>1524-6175 (Linking) |
| Accession Number | 22277138 |
| Keywords | Adult, Alaska/epidemiology, Coronary Artery Disease/ epidemiology/ genetics, Female, Glomerular Filtration Rate, Humans, Hypertension/ blood/ ethnology, Inuits, Linear Models, Logistic Models, Male, Middle Aged, Renal Insufficiency, Chronic/ blood/ ethnology, Uric Acid/ blood, Young Adult |
| Abstract | It is unknown what role uric acid (UA) may play in the increasing rates of cardiovascular disease (CVD) among Alaska Eskimos. UA is associated with both hypertension (HTN) and chronic kidney disease (CKD). The authors analyzed 1078 Genetics of Coronary Artery Disease in Alaska Natives (GOCADAN) participants. Estimated glomerular filtration rate (eGFR) was calculated from serum creatinine measures using the Modification of Diet in Renal Disease equation. CKD was defined by an eGFR of |
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