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Greater hand-grip strength predicts a lower risk of developing type 2 diabetes over 10 years in leaner Japanese Americans

TitleGreater hand-grip strength predicts a lower risk of developing type 2 diabetes over 10 years in leaner Japanese Americans
Publication TypeJournal Article
Year of Publication2011
AuthorsWander, PL, Boyko, EJ, Leonetti, DL, McNeely, MJ, Kahn, SE, Fujimoto, WY
JournalDiabetes Research & Clinical PracticeDiabetes Research & Clinical Practice
Volume92
Pagination261-264
ISBN Number0168-8227
KeywordsAdult, Aged, Asians -- Statistics and Numerical Data, Body Composition -- Physiology, Body Mass Index, Diabetes Mellitus, Type 2 -- Epidemiology, Female, Grip Strength -- Physiology, Logistic Regression, Male, Middle Age, Risk Factors
AbstractAIMS: Much is known about body composition and type 2 diabetes risk but less about body function such as strength. We assessed whether hand-grip strength predicted incident diabetes. METHODS: We followed 394 nondiabetic Japanese-American subjects (mean age 51.9) for the development of diabetes. We fit a logistic regression model to examine the association between hand-grip strength at baseline and type 2 diabetes risk over 10 years, adjusted for age, sex, and family history. RESULTS: A statistically significant (p=0.008) and negative (coefficient -0.208) association was observed between hand-grip strength and diabetes risk that diminished at higher BMI levels. Adjusted ORs for a 10-pound hand-grip strength increase with BMI set at the 25th, 50th or 75th percentiles were 0.68, 0.79, and 0.98, respectively. CONCLUSIONS: Among leaner individuals, greater hand-grip strength was associated with lower risk of type 2 diabetes, suggesting it may be a useful marker of risk in this population.
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