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Frailty and incidence of activities of daily living disability among older Mexican Americans

TitleFrailty and incidence of activities of daily living disability among older Mexican Americans
Publication TypeJournal Article
Year of Publication2009
AuthorsS. Snih, A, Graham, JE, Ray, LA, Samper-Ternent, R, Markides, KS, Ottenbacher, KJ
JournalJ Rehabil MedJ Rehabil Med
Date PublishedNov
ISBN Number1651-2081 (Electronic)<br/>1650-1977 (Linking)
Accession Number19841840
KeywordsAged, Disability Evaluation, Female, Follow-Up Studies, Frail Elderly/psychology, Hand Strength/physiology, Humans, Male, Mexican Americans, Prospective Studies, Risk Factors, Socioeconomic Factors, Weight Loss/physiology
AbstractOBJECTIVE: To examine the association between frailty status and incidence of disability among non-disabled older Mexican Americans. DESIGN: A 10-year prospective cohort study. SUBJECTS: A total of 1645 non-institutionalized Mexican Americans aged 67 years and older from the Hispanic Established Population for the Epidemiological Study of the Elderly (H-EPESE), who reported no limitation in activities of daily living at baseline. METHODS: Frailty was defined as meeting 3 or more of the following components: (i) unintentional weight loss of > 2.26 kg; (ii) weakness (lowest 20% in hand grip strength); (iii) self-reported exhaustion; (iv) slow walking speed; and (v) low physical activity level. Socio-demographic factors, Mini Mental State Examination, medical conditions, body mass index, and self-reported activities of daily living were obtained. RESULTS: Of the 1645 non-disabled subjects at baseline, 820 (50%) were not frail, 749 (45.7%) were pre-frail, and 71 (4.3%) were frail. The hazard ratio of activities of daily living disability at 10-year follow-up for pre-frail subjects was 1.32 (95% confidence interval 1.10-1.58) and 2.42 (95% confidence interval 70-3.46) for frail subjects compared with not frail subjects. This association remained statistically significant after controlling for potential confounding factors at baseline. CONCLUSION: Pre-frail and frail status in older Mexican Americans was associated with an increased risk of activities of daily living disability over a 10-year period among non-disabled subjects.