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Elevated depressive symptoms and incident stroke in Hispanic, African-American, and White older Americans

TitleElevated depressive symptoms and incident stroke in Hispanic, African-American, and White older Americans
Publication TypeJournal Article
Year of Publication2012
AuthorsGlymour, MM, Yen, JJ, Kosheleva, A, Moon, JR, Capistrant, BD, Patton, KK
JournalJ Behav MedJ Behav Med
Date PublishedApr
ISBN Number1573-3521 (Electronic)<br/>0160-7715 (Linking)
Accession Number21656258
KeywordsAfrican Americans/ statistics & numerical data, Age Factors, Aged, Depression/ epidemiology, European Continental Ancestry Group/ statistics & numerical data, Female, Health Surveys, Hispanic Americans/ statistics & numerical data, Humans, Incidence, Longitudinal Studies, Male, Middle Aged, Predictive Value of Tests, Prevalence, Risk Factors, Stroke/ epidemiology, United States/epidemiology
AbstractAlthough depressive symptoms have been linked to stroke, most research has been in relatively ethnically homogeneous, predominantly white, samples. Using the United States based Health and Retirement Study, we compared the relationships between elevated depressive symptoms and incident first stroke for Hispanic, black, or white/other participants (N = 18,648) and estimated the corresponding Population Attributable Fractions. The prevalence of elevated depressive symptoms was higher in blacks (27%) and Hispanics (33%) than whites/others (18%). Elevated depressive symptoms prospectively predicted stroke risk in the whites/other group (HR = 1.53; 95% CI: 1.36-1.73) and among blacks (HR = 1.31; 95% CI: 1.05-1.65). The HR was similar but only marginally statistically significant among Hispanics (HR = 1.33; 95% CI: 0.92-1.91). The Population Attributable Fraction, indicating the percent of first strokes that would be prevented if the incident stroke rate in those with elevated depressive symptoms was the same as the rate for those without depressive symptoms, was 8.3% for whites/others, 7.8% for blacks, and 10.3% for Hispanics.