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Depressive symptoms and cardiovascular mortality in older black and white adults: evidence for a differential association by race

TitleDepressive symptoms and cardiovascular mortality in older black and white adults: evidence for a differential association by race
Publication TypeJournal Article
Year of Publication2011
AuthorsLewis, TT, Guo, H, Lunos, S, de Leon, CFMendes, Skarupski, KA, Evans, DA, Everson-Rose, SA
JournalCirc Cardiovasc Qual OutcomesCirc Cardiovasc Qual Outcomes
Volume4
Pagination293-9
Date PublishedMay
ISBN Number1941-7705 (Electronic)<br/>1941-7713 (Linking)
Accession Number21505153
KeywordsAfrican Continental Ancestry Group, Aged, Aged, 80 and Over, Cardiovascular Diseases/ epidemiology/ethnology/ mortality, Depression/ complications/ethnology, European Continental Ancestry Group, Female, Follow-Up Studies, Humans, Longitudinal Studies, Male, Myocardial Ischemia/epidemiology/ethnology/mortality, Proportional Hazards Models, Risk Factors, Stroke/epidemiology/ethnology/mortality, Survival Rate
AbstractBACKGROUND: An emerging body of research suggests that depressive symptoms may confer an "accelerated risk" for cardiovascular disease (CVD) in blacks compared with whites. Research in this area has been limited to cardiovascular risk factors and early markers; less is known about black-white differences in associations with important clinical end points. METHODS AND RESULTS: The authors examined the association between depressive symptoms and overall CVD mortality, ischemic heart disease (IHD) mortality, and stroke mortality in a sample of 6158 (62% black; 61% female) community-dwelling older adults. Cox proportional hazards models were used to model time-to-CVD, IHD, and stroke death over a 9- to 12-year follow-up. In race-stratified models adjusted for age and sex, elevated depressive symptoms were associated with CVD mortality in blacks (hazard ratio [HR], 1.95; 95% confidence interval [CI], 1.61 to 2.36; P
Short TitleCirculation. Cardiovascular quality and outcomes
Ethno Med: