| Title | Better glycemic control is associated with maintenance of lower-extremity function over time in Mexican American and European American older adults with diabetes |
| Publication Type | Journal Article |
| Year of Publication | 2011 |
| Authors | Wang, CP, Hazuda, HP |
| Journal | Diabetes CareDiabetes Care |
| Volume | 34 |
| Pagination | 268-73 |
| Date Published | Feb |
| ISBN Number | 1935-5548 (Electronic)<br/>0149-5992 (Linking) |
| Accession Number | 21216857 |
| Keywords | Activities of Daily Living, Aged, Aged, 80 and Over, Aging, Diabetes Complications/drug therapy/ ethnology, Disability Evaluation, European Continental Ancestry Group/ statistics & numerical data, Female, Humans, Hyperglycemia/drug therapy/ ethnology, Incidence, Leg, Longitudinal Studies, Male, Mexican Americans/ statistics & numerical data, Mobility Limitation, Motor Activity, Prevalence |
| Abstract | OBJECTIVE: Diabetes is a major cause of functional decline among older adults, but the role of glycemic control remains unclear. This article assesses whether better glycemic control is associated with better maintenance of lower-extremity function over time in older adults with diabetes. RESEARCH DESIGN AND METHODS: Participants (n = 119) in the San Antonio Longitudinal Study of Aging, ages 71-85, who met American Diabetes Association diabetes criteria were followed over a 36-month period. Seven measures of A1C (HbA(1c)) were obtained at 6-month intervals; three measures of lower-extremity function were obtained at 18-month intervals using the Short Physical Performance Battery (SPPB). A two-step analytic approach was used, first, to identify distinct glycemic control classes using latent growth mixture modeling and, second, to examine trajectories of lower-extremity function based on these classes using path analysis. RESULTS: Two glycemic control classes were identified: a poorer control class with higher means (all >7%) and higher within-subject variability in HbA(1c) and a better control class with lower means (all |
Ethno Med: