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The association of blood pressure and mortality differs by self-reported walking speed in older Latinos

TitleThe association of blood pressure and mortality differs by self-reported walking speed in older Latinos
Publication TypeJournal Article
Year of Publication2012
AuthorsOdden, MC, Covinsky, KE, Neuhaus, JM, Mayeda, ER, Peralta, CA, Haan, MN
JournalJ Gerontol A Biol Sci Med SciJ Gerontol A Biol Sci Med Sci
Date PublishedSep
ISBN Number1758-535X (Electronic)<br/>1079-5006 (Linking)
Accession Number22389463
KeywordsAged, Aged, 80 and Over, Aging/ physiology, Blood Pressure, California/epidemiology, Cohort Studies, Female, Frail Elderly, Humans, Hypertension/epidemiology/mortality/physiopathology, Longitudinal Studies, Male, Mexican Americans, Middle Aged, Mortality, Proportional Hazards Models, Risk Factors, Self Report, Walking
AbstractBACKGROUND: In some older adults, higher blood pressure (BP) is associated with a lower risk of mortality. We hypothesized that higher BP would be associated with greater mortality in high-functioning elders and lower mortality in elders with lower functional status. METHODS: Participants were 1,562 Latino adults aged 60-101 years in the Sacramento Area Latino Study on Aging. Functional status was measured by self-reported walking speed, and BP was measured by automatic sphygmomanometer. Death information was determined from vital statistics records. RESULTS: There were 442 deaths from 1998 to 2010; 53% were cardiovascular. Mean BP levels (mmHg) varied across fast, medium, and slow walkers: 136, 139, and 140 mmHg (systolic), p = .02 and 75, 76, and 77 mmHg (diastolic), p = .08, respectively. The relationship between systolic BP and mortality varied by self-reported walking speed: The adjusted hazard ratio for mortality in slow walkers was 0.96 per 10 mmHg higher systolic BP (95% confidence interval: 0.89, 1.02) and 1.29 (95% confidence interval: 1.08, 1.55) in fast walkers (p value for interaction <.001 we="" found="" a="" similar="" pattern="" for="" diastolic="" bp="" although="" the="" interaction="" did="" not="" reach="" statistical="" significance="" adjusted="" hazard="" ratio="" per="" mmhg="" higher="" was="" confidence="" interval:="" in="" slow="" walkers="" and="" fast="" value="" conclusions:="" high-functioning="" older="" adults="" elevated="" systolic="" is="" risk="" factor="" all-cause="" mortality.="" if="" confirmed="" other="" studies="" assessment="" of="" functional="" status="" may="" help="" to="" identify="" persons="" who="" are="" most="" at-risk="" adverse="" outcomes="" related="" high="" bp.="">