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Are depressive symptoms a risk factor for mortality in elderly Japanese American men?: The Honolulu-Asia Aging Study

TitleAre depressive symptoms a risk factor for mortality in elderly Japanese American men?: The Honolulu-Asia Aging Study
Publication TypeJournal Article
Year of Publication2002
AuthorsTakeshita, J, Masaki, K, Ahmed, I, Foley, DJ, Li, YQing, Chen, R, Fujii, D, Ross, G, Petrovich, H, White, L
JournalThe American Journal of PsychiatryThe American Journal of Psychiatry
Volume159
Pagination1127-1132
Date PublishedJul
ISBN Number0002-953X<br/>1535-7228
Accession NumberPeer Reviewed Journal: 2002-15165-009
Keywords*At Risk Populations, *Death and Dying, *Demographic Characteristics, *Major Depression, *Risk Factors, Affective Disorders [3211], Human Male Adulthood (18 yrs & older) Aged (65 yrs & older) Very Old (85 yrs & older), Human Males, Japanese Americans, mortality, depressive symptoms, Japanese American men, risk factors, symptoms, us
AbstractThis study determined the influence of depressive symptoms on subsequent mortality of all causes. The analysis was based on 3,196 Japanese American men aged 71-93 in 1991-1993 as part of the Honolulu Heart Program, a prospective, community-based cohort. The overall prevalence of frequent depressive symptoms was 9.9%. Age-adjusted mortality rates at 3 yrs were 48.0 and 30.3 per 1,000 person-years for the depressed and nondepressed groups, respectively. At 6 yrs, the rates were 54.1 (depressed) and 41.5 (nondepressed) per 1,000 person-years. After adjustment for age, marital status, and antidepressant use, the relative risk for all-cause mortality associated with depressive symptoms was 1.53 for 3-yr and 1.27 for 6-yr mortality. Among participants who were healthy, the association between depressive symptoms and mortality was greater. Depressive symptoms are a risk factor for mortality in elderly people, particularly in physically healthy adults. (PsycINFO Database Record (c) 2012 APA, all rights reserved).
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