| Title | Albuminuria among Alaska Natives--findings from the Genetics of Coronary Artery Disease in Alaska Natives (GOCADAN) study |
| Publication Type | Journal Article |
| Year of Publication | 2010 |
| Authors | Jolly, SE, Noonan, CJ, Roubideaux, YD, Goldberg, JH, Ebbesson, SO, Umans, JG, Howard, BV |
| Journal | Nephron Clin PractNephron Clin Pract |
| Volume | 115 |
| Pagination | c107-13 |
| ISBN Number | 1660-2110 (Electronic)<br/>1660-2110 (Linking) |
| Accession Number | 20407273 |
| Keywords | Adolescent, Adult, Aged, Aged, 80 and Over, Alaska/ethnology, Albuminuria/complications/ ethnology/ genetics, Coronary Artery Disease/complications/ ethnology/ genetics, Cross-Sectional Studies, Diabetes Mellitus/ethnology/genetics, Female, Humans, Hypertension/complications/ethnology/genetics, Indians, North American/ ethnology/ genetics, Male, Middle Aged, Risk Factors, Young Adult |
| Abstract | BACKGROUND: The prevalence and associated risk factors for albuminuria and low-grade albuminuria in Alaska Natives is not known. METHODS: Cross-sectional analysis of the Genetics of Coronary Artery Disease in Alaska Natives Study. We included 1,026 individuals, who represent 85% of the study participants for whom complete data were available. Risk factors examined were age, sex, education, diabetes, hypertension, obesity, lipids, C-reactive protein, angiotensin-converting enzyme inhibitor use, and smoking status. Urine albumin excretion was estimated by the albumin/creatinine ratio measured from a single random morning urine sample. Albuminuria was defined as an albumin/creatinine ratio of > or =30 mg/g. Low-grade albuminuria was defined as an albumin/creatinine ratio of 10 to |
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